Companies and other large organizations are increasingly being asked by investors, customers, employees, and policymakers to set Science-Based Targets (SBTs) for reducing their climate impacts in line with the goal of limiting global warming to well below 2-degrees Celsius. Science-based targets require that organizations address emissions generated by their own operations and those of their suppliers, which can contribute the majority of their emissions. This session will share Mastercard’s rationale for setting a science-based target, how it got to know which suppliers accounted for the largest share of emissions, and how it began the emissions reductions conversation with key supplier partners. The session will provide valuable guidance to other organizations considering a similar journey.